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Dr. Paul Garris

Distinguished Professor Emeritus
School of Biological Sciences
Office
FSA Felmley Hall of Science Annex 233
  • About
  • Education
  • Research

Biography

B.A. Religion. Earlham College. Richmond, IN. 1983

Ph.D. Physiology and Biophysics. Indiana University School of Medicine. Indianapolis, IN. 1990

Postdoctoral Associate. Analytical Chemistry. University of North Carolina. 1990-1995

Current Courses

BSC 290.013 Research In Biological Sciences

Teaching Interests & Areas

Neuroscience; Animal Physiology; General Biology

Research Interests & Areas

Drugs of abuse; Parkinson's disease; attention deficit hyperactivity disorder; microsensor instrumentation development

Post-Doc Analytical Chemistry

University of North Carolina

Ph D Physiology and Biophysics

Indiana University School of Medicine
Indianapolis, IN

BA Religion

Earlham College
Richmond, IN

Grants & Contracts

Therapeutic psychostimulants, associative learning, and dopamine function. URG FRA. Illinois State University. (2017)

Book, Chapter

Garris, P., & Keefe, K. Voltammetric analysis of loss and gain of dopamine function. Wilson GS and Michael AC (EDs), Compendium of In Vivo Monitoring in Real-Time Molecular Neuroscience. World Scientific Publishing Co 1 (2014): 287-309.
Covey, D., Bennet, K., Blaha, C., Mohseni, M., Lee, K., & Garris, P. Technological evolution of wireless neurochemical sensing with fast-scan cyclic voltammetry. Iniewski K (EDs), Integrated Microsystems and Nanotechnology. Artech House (2011): 174-164.
Sandberg, S., & Garris, P. Neurochemistry of addiction: monitoring essential neurotransmitters of addiction. Kuhn CM and Koob GF (EDs), Frontiers in the Neurobiology of Addiction. CRC Press (2010): 101-136.

Conference Proceeding

Roham, M., Covey, D., Daberkow, D., Ramsson, E., Howard, C., Garris, P., & Mohseni, P. An implanted device for wireless FSCV monitoring of dopamine in an ambulatory subject. Conf. Proc. IEEE Eng. Med. Biol. Soc. (2010): 5322-5325.
Covey, D., & Garris, P. Using fast-scan cyclic voltammetry to evaluate striatal dopamine release elicited by subthalamic nucleus stimulation. Conf. Proc. IEEE Eng Med. Biol. Soc. (2009): 3306-3309.
Kimble, C., Johnson, D., Winter, B., Whitlock, S., Kressin, K., Home, A., Robinson, J., Bledsoe, J., Tye, S., Chang, S., Agnesi, F., Griessenauer, C., Covey, D., Shon, Y., Bennet, K., Garris, P., & Lee, K. Wireless instantaneous neurotransmitter concentration sensing system (WINCS) for intraoperative neurochemical monitoring. Conf. Proc. IEEE Eng Med. Biol. Soc (2009): 4856-4859.
Roham, M., Blaha, C., Garris, P., Lee, K., & Mohseni, P. A configurable IC for wireless real-time in vivo monitoring of chemical and electrical neural activity. Conf. Proc. IEEE Eng Med. Biol. Soc (2009): 4222-4225.
Roham, M., Garris, P., & Mohseni, P. A wireless IC for time-share chemical and electrical neural recording. IEEE Int Solid-state Circuits Conference (2009): 430-431.

Journal Article

Zamani, H., Bahrami, H., Garris, P., & Mohseni, P. Compressed Principal Component Regression (C-PCR) Algorithm and FPGA Validation. IEEE Transactions on Circuits and Systems II: Express Briefs 67 (2020): 3512-3516.
Schuweiler, D., Athens, J., Thompson, J., Vazhayil, S., & Garris, P. Effects of an acute therapeutic or rewarding dose of amphetamine on acquisition of Pavlovian autoshaping and ventral striatal dopamine signaling. Behavioural Brain Research 336 (2018): 191-203.
Schuweiler, D., Howard, C., Ramsson, E., & Garris, P. Improving in situ electrode calibration with principal component regression for fast-scan cyclic voltammetry. Analytical Chemistry 90 (2018): 13434-13442.
Zamani, H., Bahrami, H., Chalwadi, P., Garris, P., & Mohseni, P. C-FSCV: Compressive fast-scan cyclic voltammetry for brain dopamine recording. Transactions on Neural Systems and Rehabilitative Engineering 26 (2018): 51-59.
Zamani, H., Bahrami, H., Garris, P., & Mohseni, P. On the use of compressive sensing (CS) for brain dopamine recording with fast-scan cyclic voltammetry (FSCV). Conf. Proc. IEEE International Conference on Semantic Computing (2017): 310-313.
Bobak, M., Weber, M., Doellman, M., Schuweiler, D., Athens, J., Juliano, S., & Garris, P. Modafinil activates phasic dopamine signaling in dorsal and ventral striata. Journal of Pharmacology and Experimental Therapeutics 359 (2016): 460-470.
Bozorgzadeh, B., Schuweiler, D., Bobak, M., Garris, P., & Mohseni, P. Neurochemostat: a neural interface SoC with integrated chemometrics for close-loop regulation of brain dopamine. IEEE Transactions on Biomedical Circuits and Systems 10 (2016): 654-667.
Covey, D., Bunner, K., Cheer, J., & Garris, P. Amphetamine elevates nucleus accumbens dopamine via an action potential-dependent mechanism that is modulated by endocannabinoids. European Journal of Neuroscience 43 (2016): 1661-1673.
Bozorgzadeh, B., Covey, D., Garris, P., & Mohseni, P. FPGA implementation of principal component regression (PCR) for real-time differentiation of dopamine from interferents. Conf. Proc. IEEE Eng. Med. Biol. Soc. (2015): 5151-5154.
Bozorgzadeh, B., Schuweiler, D., Bobak, M., Garris, P., & Mohseni, P. Neurochemical thermostat: a neural interface SoC with integrated chemometrics for close-loop regulation of brain dopamine. Dig. Tech. Papers IEEE Symp. VLSI Circuits (2015): 110-111.
Smith, A., Garris, P., & Casto, J. Real-time monitoring of electrically evoked catecholamine signals in the songbird striatum using in vivo fast-scan cyclic voltammetry. Journal of Chemical Neuroanatomy 66-67 (2015): 28-39.
Bozorgzadeh, B., Covey, D., Howard, C., Garris, P., & Mohseni, P. A neurochemical pattern generator SoC with switched-electrode management for single-chip electrical stimulation and 9.3µW, 78pArms, 400V/s FSCV sensing. IEEE Journal of Solid-State Circuits 49 (2014): 881-895.
Bozorgzadeh, B., Covey, D., Heidenreich, PhD, B., Garris, P., & Mohseni, P. Real-time processing of fast-scan cyclic voltammetry (FSCV) data using a field-programmable gate array (FPGA). Conf. Proc. IEEE Eng. Med. Biol. Soc. (2014): 2036-3039.
Covey, D., & Garris, P. Illicit dopamine transients: reconciling actions of abused drugs. Trends in Neurosciences 37 (2014): 200-210.
Robinson, J., Christopher, H., Byers, D., Pastuzyn, E., Keefe, K., & Garris, P. Methamphetamine-induced neurotoxicity disrupts pharmacologically evoked dopamine transients in the dorsomedial and dorsolateral striatum. Neurotoxicity Research 26 (2014): 152-167.
Arumugam, P., Zeng, H., Siddiqui, S., Covey, D., & Garris, P. Characterization of ultrananocrystalline diamond microsensors for in vivo dopamine detection. Applied Physics Letters 102 (2013): 253107(1-5).
Avelar , A., Juliano, S., & Garris, P. Amphetamine augments vesicular dopamine release in the dorsal and ventral striatum through different mechanisms. Journal of Neurochemistry. Journal of Neurochemistry 125 (2013): 373-385.
Bozorgzadeh, B., Covey, D., Howard, C., Garris, P., & Mohseni, P. A neurochemical pattern generator SoC with switched-electrode management for single-chip electrical stimulation and 9.3µW, 78pArms, 400V/s FSCV sensing. Dig. Tech. Papers IEEE Symp. VLSI Circuits C-1 (2013): 50-51.
Daberkow, D., Brown, H., Bunner, K., Kraniotis, S., Doellman, M., Ragozino, M., Garris, P., & Roitman, M. Amphetamine paradoxically augments exocytotic dopamine release and phasic dopamine signals.. Journal of Neuroscience 33 (2013): 452-463.
Dan, C., Juliano, J., & Garris, P. Amphetamine elicits opposing actions on readily releasable and reserve pools for dopamine. PLoS 8 (2013): e60763.
Howard, C., Daberkow, D., Ramsson, E., Keefe, K., & Garris, P. Methamphetamine-induced neurotoxicity disrupts naturally occuring phasic dopamine signaling. European Journal of Neuroscience 38 (2013): 2078-2088.
Howard, C., Pastuzyn, E., Barker-Halisk, M., Garris, P., & Keefe, K. Phasic-like stimulation of the medial forebrain bundle augments striatal gene expression despite methamphetamine-induced partial dopamine denervation. Journal of Neurochemistry 125 (2013): 555-565.
Chang, S., Kim, I., Marsh, M., Jang, D., Hwang, S., Van Gompel, J., Goerss, S., Kimble, C., Bennet, K., Garris, P., Blaha, C., & Lee, K. Wireless fast-scan cyclic voltammetry to monitor adenosine in patients with essential tremor during deep brain stimulation. Mayo Clinic Proceedings 87 (2012): 760-765.
Bergstrom, B., Sandberg, S., Andersson, M., Mithyantha, J., Carroll, F., & Garris, P. Functional reorganization of the presynaptic dopaminergic terminal in parkinsonism. Neuroscience (2011): 310-322.
Howard, C., Keefe, K., Garris, P., & Daberkow, D. Methamphetamine neurotoxicity decreases phasic, but not tonic, dopaminergic signaling in the rat striatum. Journal of Neurochemistry (2011): 668-676.
Ramsson, E., Covey, D., Daberkow, D., Litherland, M., Juliano, S., & Garris, P. Amphetamine augments action potential-dependent dopaminergic signaling in the striatum in vivo. Journal of Neurochemistry (2011): 937-948.
Ramsson, E., Howard, C., Covey, D., & Garris, P. High doses of amphetamine augment, rather than disrupt, exocytotic dopamine release in the dorsal and ventral striatum of the anesthetized rat. Journal of Neurochemistry (2011): 1162-1172.
Addy, N., Daberkow, D., Ford, J., Garris, P., & Wightman, R. Sensitization of rapid dopamine signaling in the nucleus accumbens core and shell after repeated cocaine in rats. Journal of Neurophysiology (2010): 922-931.
Garris, P. Advancing Neurochemical Monitoring. Nature Methods (2010): 106-108.
Griessenauer, C., Chang, S., Tye, S., Kimble, C., Bennet, K., Garris, P., & Lee, K. Wireless instantaneous neurotransmitter system: electrochemical monitoring of serotonin using fast-scan cyclic voltammetry – a proof-of-principle study. Journal of Neurosurgery (2010): 656-665.
Agnesi, F., Tye, S., Bledsoe, J., Griessenauer, C., Kimble, C., Sieck, G., Bennet, K., Garris, P., Blaha, C., & Lee, K. Wireless instantaneous neurotransmitter concentration system-based amperometric detection of dopamine, adenosine, and glutamate for intraoperative neurochemical monitoring. Journal of Neurosurgery (2009): 701-711.
Bledsoe, J., Kimble, C., Covey, D., Blaha, C., Agnesi, F., Whitlock, S., Johnson, D., Bennet, K., Lee, K., & Garris, P. Development of wireless instantaneous neurotransmitter concentration system (WINCS) for intraoperative neurochemical monitoring using fast-scan cyclic voltammetry. Journal of Neurosurgery (2009): 712-723.
Kraft, J., Osterhaus, G., Ortiz, A., Garris, P., & Johnson, M. In vivo dopamine release and uptake impairments in rats treated with 3-nitropropionic acid. Neuroscience (2009): 940-9.
Lee, K., Blaha, C., Garris, P., Mohseni, P., Horne, A., Bennet, K., Agnesi, F., Bledsoe, J., Lester, D., Kimble, C., Min, H., Kim, Y., & Cho, Z. Evolution of deep brain stimulation: human electrometer and smart devices supporting the next generation of therapy. Neuromodulation (2009): 85-103.

Other

Lee, K., Chang, S., Jang, D., Kim, I., Goerss, S., Van Gompel, J., Min, P., Arora, K., Marsh, M., Hwang, S., Kimble, C., Garris, P., Blaha, C., & Bennet, K. Emerging techniques for elucidating mechanism of action of Deep Brain Stimulation. Conf. Proc. IEEE Eng. Med. Biol. Soc. (2011): 677-680.